Plasmid-Mediated qnrB2 and Carbapenemase Gene bla KPC-2 Carried on the Same Plasmid in Carbapenem-Resistant Ciprofloxacin-Susceptible Enterobacter cloacae Isolates-Reference-Cited by-同舟云学术

Plasmid-Mediated qnrB2 and Carbapenemase Gene bla KPC-2 Carried on the Same Plasmid in Carbapenem-Resistant Ciprofloxacin-Susceptible Enterobacter cloacae Isolates

Published:2008-08 Issue:8 Volume:52 Page:2962-2965
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Chmelnitsky Inna¹,Navon-Venezia Shiri¹,Strahilevitz Jacob²,Carmeli Yehuda¹

Affiliation:

1. Division of Epidemiology, Tel-Aviv Medical Center, Tel Aviv, Israel

2. Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University, Jerusalem

Abstract

ABSTRACT Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and bla KPC-2 genes encoded on the same plasmid. One isolate also carried the aac(6 ′)- Ib-cr gene. Coexistence of quinolone resistance determinants and bla KPC-2 on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01341-07

Reference26 articles.

1. Barton, B. M., G. P. Harding, and A. J. Zuccarelli. 1995. A general method for detecting and sizing large plasmids. Anal. Biochem.226:235-240.

2. Baucheron, S., H. Imberechts, E. Chaslus-Dancla, and A. Cloeckaert. 2002. The AcrB multidrug transporter plays a major role in high-level fluoroquinolone resistance in Salmonella enterica serovar Typhimurium phage type DT204. Microb. Drug Resist.8:281-289.

3. Bratu, S., P. Tolaney, U. Karumudi, J. Quale, M. Mooty, S. Nichani, and D. Landman. 2005. Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents. J. Antimicrob. Chemother.56:128-132.

4. Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates

5. Cloning of a Novel Gene for Quinolone Resistance from a Transferable Plasmid in Shigella flexneri 2b

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Characterization of resistance mechanisms of Enterobacter cloacae Complex co-resistant to carbapenem and colistin;BMC Microbiology;2021-07-08

2. On-Site Genomic Epidemiological Analysis of Antimicrobial-Resistant Bacteria in Cambodia With Portable Laboratory Equipment;Frontiers in Microbiology;2021-05-13

3. On-site genomic epidemiological analysis of antimicrobial-resistant bacteria in Cambodia with portable laboratory equipment;2021-03-03

4. Molecular characterisation of carbapenem-resistant Enterobacter cloacae complex in Colombia: bla KPC and the ‘changing landscape’;Journal of Global Antimicrobial Resistance;2018-06

5. ANTIMICROBIAL SUSCEPTIBILITY OF CLINICALLY SIGNIFICANT ISOLATES OF ENTEROBACTER SPP., OBTAINED FROM PATIENTS, HOSPITALISED IN VARNA UNIVERSITY HOSPITAL DURING THE PERIOD 2014 – 2016;Journal of IMAB - Annual Proceeding (Scientific Papers);2017-12-18