Increased Sensitivity to Oxidative Challenges Associated with topA Deletion in Escherichia coli-Reference-Cited by-同舟云学术

Increased Sensitivity to Oxidative Challenges Associated with topA Deletion in Escherichia coli

Published:2000-02 Issue:3 Volume:182 Page:829-832
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Tse-Dinh Yuk-Ching¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York 10595

Abstract

ABSTRACT Deletion of topA in Escherichia coli was found to result in a higher level of killing after treatment with either hydrogen peroxide or N -ethylmaleimide. This effect on oxidative challenge response represents a new role for E. coli DNA topoisomerase I in addition to prevention of excessive negative supercoiling of DNA.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.182.3.829-832.2000

Reference33 articles.

1. The dps promoter is activated by OxyR during growth and by IHF and ςS in stationary phase;Altuvia S.;Mol. Microbiol.,1994

2. Regulation of bacterial oxidative stress genes;Demple B.;Annu. Rev. Genet.,1991

3. Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes;DiNardo S.;Cell,1982

4. Flexible response: DNA supercoiling, transcription and bacterial adaptation to environmental stress

5. Control of bacterial DNA supercoiling

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