Diversity of the P2 protein among nontypeable Haemophilus influenzae isolates-Reference-Cited by-同舟云学术

Diversity of the P2 protein among nontypeable Haemophilus influenzae isolates

Published:1994-06 Issue:6 Volume:62 Page:2639-2643
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Bell J¹,Grass S¹,Jeanteur D¹,Munson R S¹

Affiliation:

1. Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.

Abstract

The genes for outer membrane protein P2 of four nontypeable Haemophilus influenzae strains were cloned and sequenced. The derived amino acid sequences were compared with the outer membrane protein P2 sequence from H. influenzae type b MinnA and the sequences of P2 from three additional nontypeable H. influenzae strains. The sequences were 76 to 94% identical. The sequences had regions with considerable variability separated by regions which were highly conserved. The variable regions mapped to putative surface-exposed loops of the protein.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.62.6.2639-2643.1994

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