Crystal Structures of Penicillin-Binding Protein D2 from Listeria monocytogenes and Structural Basis for Antibiotic Specificity-Reference-Cited by-同舟云学术

Crystal Structures of Penicillin-Binding Protein D2 from Listeria monocytogenes and Structural Basis for Antibiotic Specificity

Published:2018-09 Issue:9 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jeong Jae-Hee¹,Cha Hyung Jin²³,Kim Yeon-Gil¹

Affiliation:

1. Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang, Republic of Korea

2. School of Biological Sciences, Seoul National University, Seoul, Republic of Korea

3. Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea

Abstract

β-Lactam antibiotics that inhibit penicillin-binding proteins (PBPs) have been widely used in the treatment of bacterial infections. However, the molecular basis underlying the different inhibitory potencies of β-lactams against specific PBPs is not fully understood.

Funder

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00796-18

Reference35 articles.

1. Peptidoglycan structure and architecture

2. Role of penicillin-binding proteins in bacterial cell morphogenesis

3. Formation of the glycan chains in the synthesis of bacterial peptidoglycan