Affiliation:
1. Institut für Virologie, Justus Liebig-Universität, Giessen, Germany
Abstract
Pseudorabies virus-induced cell fusion in rabbit kidney cells can be prevented by Concanavalin A added early after infection. The infected cells are not agglutinated and the infectivity of cell-free virus is not reduced. Sera from productively infected animals also inhibit polykaryocytosis, whereas a hyperimmune serum directed against virus structural components has no effect. 2-Deoxy-
d
-glucose reversibly disturbs virus-induced fusion and reduces significantly the virus infectivity.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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