Enterococcus faecalis OG1RF Evolution at Low pH Selects Fusidate-Sensitive Mutants in Elongation Factor G and at High pH Selects Defects in Phosphate Transport-Reference-Cited by-同舟云学术

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Enterococcus faecalis OG1RF Evolution at Low pH Selects Fusidate-Sensitive Mutants in Elongation Factor G and at High pH Selects Defects in Phosphate Transport

Published:2023-06-28 Issue:6 Volume:89 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Fitzgerald Bailey A.¹,Wadud Ayman¹,Slimak Zachary¹,Slonczewski Joan L.¹^ORCID

Affiliation:

1. Department of Biology, Kenyon College, Gambier, Ohio, USA

Abstract

E. faecalis bacteria are found in dental biofilms, where they experience low pH as a result of fermentative metabolism. Thus, the effect of pH on antibiotic resistance has clinical importance.

Funder

National Science Foundation

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.00466-23

Reference62 articles.

1. The rise of the Enterococcus: beyond vancomycin resistance

2. Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF

3. Lebreton F Willems RJL Gilmore MS. 2014. Enterococcus diversity origins in nature and gut colonization. Enterococci: from commensals to leading causes of drug resistant infection. http://www.ncbi.nlm.nih.gov/pubmed/24649513.

4. Enterococci and Their Interactions with the Intestinal Microbiome

5. Enterococcus plantarum sp. nov., isolated from plants

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