MAPK-Activated Transcription Factor PxJun Suppresses PxABCB1 Expression and Confers Resistance to Bacillus thuringiensis Cry1Ac Toxin in Plutella xylostella (L.)-Reference-Cited by-同舟云学术

MAPK-Activated Transcription Factor PxJun Suppresses PxABCB1 Expression and Confers Resistance to Bacillus thuringiensis Cry1Ac Toxin in Plutella xylostella (L.)

Published:2021-06-11 Issue:13 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Qin Jianying¹²,Guo Le²,Ye Fan²,Kang Shi²,Sun Dan²,Zhu Liuhong²,Bai Yang²,Cheng Zhouqiang²,Xu Linzheng²,Ouyang Chunzheng²,Xiao Lifeng²,Wang Shaoli²,Wu Qingjun²,Zhou Xuguo³,Crickmore Neil⁴,Zhou Xiaomao¹,Guo Zhaojiang²^ORCID,Zhang Youjun²^ORCID

Affiliation:

1. Longping Branch, Graduate School of Hunan University, Changsha, China

2. Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China

3. Department of Entomology, University of Kentucky, Lexington, Kentucky, USA

4. School of Life Sciences, University of Sussex, Brighton, United Kingdom

Abstract

The transcriptional regulation mechanisms underlying reduced expression of B. thuringiensis toxin receptor genes in B. thuringiensis -resistant insects remain elusive. This study unveils that a transcription factor PxJun activated by the MAPK signaling pathway represses PxABCB1 expression and confers Cry1Ac resistance in P. xylostella .

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00466-21

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