Legionella pneumophila CRISPR-Cas Suggests Recurrent Encounters with One or More Phages in the Family Microviridae-Reference-Cited by-同舟云学术

Legionella pneumophila CRISPR-Cas Suggests Recurrent Encounters with One or More Phages in the Family Microviridae

Published:2021-08-11 Issue:17 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Deecker Shayna R.¹,Urbanus Malene L.¹,Nicholson Beth¹,Ensminger Alexander W.¹²^ORCID

Affiliation:

1. Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Abstract

Legionnaires’ disease is an often-fatal pneumonia caused by Legionella pneumophila , which normally grows inside amoebae and other freshwater protists. L. pneumophila trades diminished access to nutrients for the protection and isolation provided by the host. One outstanding question is whether L. pneumophila is susceptible to phages, given the protection provided by its intracellular lifestyle.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00467-21

Reference97 articles.

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2. Ecology of Legionella: From data to knowledge with a little wisdom

3. Confirmed and Potential Sources of Legionella Reviewed