Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis-Reference-Cited by-同舟云学术

Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis

Published:1993-02 Issue:2 Volume:37 Page:357-359
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Boivin G¹,Erice A¹,Crane D D¹,Dunn D L¹,Balfour H H¹

Affiliation:

1. Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis 55455.

Abstract

We determined the acyclovir (ACV) susceptibilities of herpes simplex virus (HSV) isolates (n = 18) recovered from solid organ transplant patients after antiviral prophylaxis with ACV or ganciclovir. All isolates tested were susceptible to ACV (50% inhibitory concentration, < 1 microM). A clinical review of patients with HSV disease showed that all improved with specific anti-HSV therapy, and no recurrences were reported.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.37.2.357

Reference20 articles.

1. Failure of prophylactic ganciclovir to prevent CMV disease in recipients of Iung transplants;Baily T. C.;J. Infect. Dis.,1992

2. A randomized, placebo-controlled trial of oral acyclovir for the prevention of CMV disease in recipients of renal allografts;Balfour H. H.;N. Engl. J. Med.,1989

3. Analysis of the thymidine kinase gene from clinically isolated acyclovir-resistant herpes simplex viruses;Chatis P. A.;Virology,1991

4. Characterization of a DNA polymerase mutant of herpes simplex virus from a severely immunocompromised patient receiving acyclovir;Collins P.;J. Gen. Virol.,1989

5. Collins P. and N. M. Oliver. 1986. Sensitivity monitoring of herpes simplex virus isolates from patients receiving acyclovir. J. Antimicrob. Chemother. 18(Suppl. B):103-112.

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