Filling in the Gaps in Metformin Biodegradation: a New Enzyme and a Metabolic Pathway for Guanylurea-Reference-Cited by-同舟云学术

Filling in the Gaps in Metformin Biodegradation: a New Enzyme and a Metabolic Pathway for Guanylurea

Published:2021-05-11 Issue:11 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Tassoulas Lambros J.¹,Robinson Ashley¹,Martinez-Vaz Betsy¹,Aukema Kelly G.¹^ORCID,Wackett Lawrence P.¹^ORCID

Affiliation:

1. Department of Biochemistry, University of Minnesota, Saint Paul, Minnesota, USA

Abstract

Metformin is a pharmaceutical most prescribed for type 2 diabetes and is now being examined for potential benefits to COVID-19 patients. People taking the drug pass it largely unchanged, and it subsequently enters wastewater treatment plants.

Funder

National Institutes of Health General Medical

USDA | National Institute of Food and Agriculture

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.03003-20

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