Cloning and Heterologous Expression of the Thioviridamide Biosynthesis Gene Cluster from Streptomyces olivoviridis-Reference-Cited by-同舟云学术

Cloning and Heterologous Expression of the Thioviridamide Biosynthesis Gene Cluster from Streptomyces olivoviridis

Published:2013-08-30 Issue:22 Volume:79 Page:7110-7113
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl. Environ. Microbiol.

Author:

Izawa Masumi,Kawasaki Takashi,Hayakawa Yoichi

Abstract

ABSTRACTThioviridamide is a unique peptide antibiotic containing five thioamide bonds fromStreptomyces olivoviridis. Draft genome sequencing revealed a gene (thetvaAgene) encoding the thioviridamide precursor peptide. The thioviridamide biosynthesis gene cluster was identified by heterologous production of thioviridamide inStreptomyces lividans.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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