Abstract
Ltk- mouse cells were transformed to thymidine kinase prototrophy in the presence of carrier DNAs isolated from different organisms. Procaryotic genomic and phage DNA was consistently less effective as a carrier than was eucaryotic DNA. Mixing experiments indicate that DNA of procaryotic origin inhibits mammalian cell transformation.
Publisher
American Society for Microbiology
Subject
Cell Biology,Molecular Biology
Cited by
9 articles.
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