Distribution of Antiseptic Resistance GenesqacA, qacB, andsmrin Methicillin-Resistant Staphylococcus aureus Isolated in Toronto, Canada, from 2005 to 2009-Reference-Cited by-同舟云学术

Distribution of Antiseptic Resistance GenesqacA, qacB, andsmrin Methicillin-Resistant Staphylococcus aureus Isolated in Toronto, Canada, from 2005 to 2009

Published:2011-03-14 Issue:6 Volume:55 Page:2999-3001
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob. Agents Chemother.

Author:

Longtin Jean,Seah Christine,Siebert Krystal,McGeer Allison,Simor Andrew,Longtin Yves,Low Donald E.,Melano Roberto G.

Abstract

ABSTRACTDecreased susceptibility to chlorhexidine gluconate (CHDN) in methicillin-resistantStaphylococcus aureus(MRSA) is associated with theqacA,qacB, andsmrgenes, encoding efflux pumps. A total of 334 MRSA isolates were collected from two Canadian intensive care units between 2005 and 2009. We identified theqacABgenes in 7 strains (2%; 2qacAgenes and 5qacBgenes) and thesmrgene in 23 (7%) strains. CHDN minimal bactericidal concentrations were slightly higher for strains harboringsmrgenes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference20 articles.

1. Analysis on distribution and genomic diversity of high-level antiseptic resistance genes qacA and qacB in human clinical isolates of Staphylococcus aureus;Alam;Microb. Drug Resist,2003

2. Efficacy and limitation of a chlorhexidine-based decolonization strategy in preventing transmission of methicillin-resistant Staphylococcus aureus in an intensive care unit;Batra;Clin. Infect. Dis,2010

3. Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients undergoing heart surgery;DeRiso;Chest,1996

4. A preliminary guideline for the assignment of methicillin-resistant Staphylococcus aureus to a Canadian pulsed-field gel electrophoresis epidemic type using spa typing;Golding;Can. J. Infect. Dis. Med. Microbiol,2008

5. Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management;Harmsen;J. Clin. Microbiol,2003

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