Establishment of Reference Values of CD4 and CD8 Lymphocyte Subsets in Healthy Nigerian Adults

Author:

Oladepo D. K.1,Idigbe E. O.2,Audu R. A.2,Inyang U. S.1,Imade G. E.3,Philip A. O.4,Okafor G. O.5,Olaleye D.6,Mohammed S. B.1,Odunukwe N. N.2,Harry T. O.7,Edyong-Ekpa M.8,Idoko J.3,Musa A. Z.2,Adedeji A.9,Nasidi A.9,Ya'aba Y.1,Ibrahim K.1

Affiliation:

1. National Institute for Pharmaceutical Research and Development, Idu, Abuja

2. Nigerian Institute of Medical Research, Yaba, Lagos

3. Jos University Teaching Hospital, Jos

4. Uthman Danfodio University Teaching Hospital, Sokoto

5. University of Nigeria Teaching Hospital, Enugu

6. University College Hospital, Ibadan

7. University of Maiduguri Teaching Hospital, Maiduguri

8. University of Uyo Teaching Hospital, Uyo

9. Federal Ministry of Health, Abuja, Nigeria

Abstract

ABSTRACT A total of 2,570 apparently healthy human immunodeficiency virus-negative adults from the six geopolitical zones in the country were enrolled in our study in 2006. The samples were assayed using the Cyflow technique. Data were analyzed using the Statistical Package for Social Scientists (SPSS). The majority (64%) of the participants had CD4 counts within the range of 501 to 1,000 cells/μl. The reference range for CD4 was 365 to 1,571 cells/μl, while the reference range for CD8 was 145 to 884 cells/μl.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference13 articles.

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