Affiliation:
1. Department of Physiological Chemistry, University of California at Los Angeles, Los Angeles, California
Abstract
Soboren, Josephine
(University of California, Los Angeles)
and Joseph F. Nyc
. Effects of certain amino acids on anthranilate production in
Neurospora crassa
. J. Bacteriol.
85:
881–888. 1963.—The level of anthranilic acid produced in cultures of a tryptophanless mutant of
Neurospora crassa
strain C-83 was closely related to the growth response. A good growth response was attained only on supplements which greatly repressed the level of anthranilate accumulated. The improved growth response of strain C-83 to variable levels of tryptophan and to supplements of the amino acids phenylalanine, tyrosine, leucine, and methionine was correlated with a decreased anthranilate production. The inhibitory effect of these supplements on anthranilate production was ascribed to effects on the mechanisms which regulate the formation of anthranilic acid.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology