Helicobacter pyloriPossesses Four Coiled-Coil-Rich Proteins That Form Extended Filamentous Structures and Control Cell Shape and Motility

Author:

Specht Mara1,Schätzle Sarah21,Graumann Peter L.1,Waidner Barbara21

Affiliation:

1. Department of Microbiology, Faculty for Biology, University of Freiburg, Schaenzle Straße 1, 79104 Freiburg, Germany

2. Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann-Herder-Straße 11, D-79104 Freiburg

Abstract

ABSTRACT We identified two additional genes of Helicobacter pylori encoding Ccrp proteins. All four Ccrps have different multimerization and filamentation properties and different types of smallest subunits and do not copurify, suggesting a system of individual Ccrp filaments. Despite the presence of morphologically unaltered flagella, all ccrp mutants displayed significantly reduced motility.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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