Mutation Profile of SARS-CoV-2 Genome Sequences Originating from Eight Israeli Patient Isolates

Author:

Zaide Galia1ORCID,Cohen-Gihon Inbar1,Israeli Ofir1,Stein Dana1,Shifman Ohad1,Weiss Shay2,Simon Irit3,Laskar Orly2,Beth-Din Adi1,Zvi Anat1ORCID

Affiliation:

1. Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel

2. Department of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel

3. Department of Biotechnology, Israel Institute for Biological Research, Ness-Ziona, Israel

Abstract

We report the genome sequences and the identification of genetic variations in eight clinical samples of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Samples were collected from nasopharyngeal swabs of symptomatic and asymptomatic individuals from five care homes for elderly and infirm persons in Israel. The sequences obtained are valuable, as they carry a newly reported nonsynonymous substitution located within the nucleoprotein open reading frame.

Funder

Israel Institute for Biological Research

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

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