Intracellular replication of Leishmania tropica in mouse peritoneal macrophages: amastigote infection of resident cells and inflammatory exudate macrophages

Author:

Fortier A H,Hoover D L,Nacy C A

Abstract

C3HeB/FeJ peritoneal exudate cells elicited by a variety of sterile inflammatory agents were exposed to Leishmania tropica amastigotes in vitro. Cytochemical characterization of cells that contained intracellular parasites suggested that young, peroxidase-positive macrophages were more susceptible to infection by amastigotes than more mature cells. Replication of the parasite in these younger cells, however, was similar to that observed in resident peritoneal macrophages.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference14 articles.

1. Studies of the macrophage complement receptor. Alteration of receptor function upon macrophage activation;Blanco C.;J. Exp. Med.,1975

2. Modification of macrophage function;Blanden R. V.;RES J. Reticuloendothel. Soc.,1968

3. Edelson P. J. 1981. Plasma membrane ectoenzymes: macrophage differentiation markers p. 143-149. In 0. Forster and M. Landy (ed.) Heterogeniety of mononuclear phagocytes. Academic Press Inc. New York.

4. 5'-Nucleotidase activity of mouse peritoneal macrophages. I. Synthesis and degradation in resident and inflammatory populations;Edelson P. J.;J. Exp. Med.,1976

5. The pinocytic rate of activated macrophages;Edelson P. J.;J. Exp. Med.,1975

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3