Affiliation:
1. Departments of Medicine and Clinical Microbiology, Health Sciences Centre
2. Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Abstract
ABSTRACT
The in vitro activity of colistin was evaluated versus 3,480 isolates of gram-negative bacilli using CLSI broth microdilution methods. The MIC
90
of colistin was ≤2 μg/ml against a variety of clinically important gram-negative bacilli, including
Escherichia coli
,
Klebsiella
spp.,
Enterobacter
spp.,
Acinetobacter baumannii
, and
Pseudomonas aeruginosa
. All multidrug-resistant (
n
= 76)
P. aeruginosa
isolates were susceptible to colistin (MIC, ≤2 μg/ml). These data support a role for colistin in the treatment of infections caused by multidrug-resistant
P. aeruginosa
.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
58 articles.
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