Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum-Reference-Cited by-同舟云学术

Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum

Published:2020-08-20 Issue:9 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Bustinduy Amaya L.¹^ORCID,Kolamunnage-Dona Ruwanthi²,Mirochnick Mark H.³,Capparelli Edmund V.⁴,Tallo Veronica⁵,Acosta Luz P.⁶,Olveda Remigio M.⁶,Friedman Jennifer F.⁷⁸,Hope William W.⁹¹⁰^ORCID

Affiliation:

1. Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom

2. Department of Biostatistics, University of Liverpool, Liverpool Health Partners, Liverpool, United Kingdom

3. Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, USA

4. Department of Pediatrics, University of California, San Diego, La Jolla, California, USA

5. Department of Epidemiology, Research Institute of Tropical Medicine, Manila, Philippines

6. Department of Immunology, Research Institute of Tropical Medicine, Manila, Philippines

7. Department of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island, USA

8. Center for International Health Research, Lifespan Hospital, Providence, Rhode Island, USA

9. Antimicrobial Pharmacodynamics and Therapeutics, University of Liverpool, Liverpool Health Partners, Liverpool, United Kingdom

10. Royal Liverpool, Broadgreen University Hospital Trust, Liverpool Health Partners, Liverpool, United Kingdom

Abstract

An estimated 40 million women of reproductive age are infected with one of three species of the waterborne parasite Schistosoma spp. Treatment with praziquantel (PZQ) via mass drug administration (MDA) campaigns is the mainstay of schistosomiasis control for populations living in areas of endemicity. The World Health Organization recommends that pregnant and lactating women be included in schistosomiasis MDA programs, and several recent studies have evaluated the safety and efficacy of PZQ use during pregnancy.

Funder

HHS | NIH | OSC | Common Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00566-20

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