Cycloheximide Production by Streptomyces griseus : Alleviation of End-Product Inhibition by Dialysis-Extraction Fermentation-Reference-Cited by-同舟云学术

Cycloheximide Production by Streptomyces griseus : Alleviation of End-Product Inhibition by Dialysis-Extraction Fermentation

Published:1975-06 Issue:6 Volume:7 Page:861-863
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Kominek L. A.¹

Affiliation:

1. Fermentation Research and Development, The Upjohn Company, Kalamazoo, Michigan 49001

Abstract

The use of dialysis fermentation with the continuous extraction of the dialysate has resulted in a twofold increase in the cycloheximide titer due to relief from product inhibition. Continuous extraction of the dialysate has eliminated the necessity for large reservoir volumes of fermentation medium normally used in dialysis fermentation. The apparatus used in this procedure is described.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.7.6.861

Reference6 articles.

1. Growth and acid production by Lactobacillus (L.) desbruechii in a dialysis culture system;Friedman M. R.;Biotech. Bioeng.,1970

2. Dialysis fermentor system for concentrated culture of microorganisms;Gallup D. M.;Appl. Microbiol.,1963

3. Dialysis flask for concentrated culture of microorganisms;Gerhardt P.;J. Bacteriol.,1963

4. Process and apparatus for dialysis fermentation;Gerhardt P.;U. S. Patent,1965

5. Differential dialysis culture for separation and concentration of a macromolecular product;Herold J. D.;Appl. Microbiol.,1967

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