Inhibition of the Classical Pathway of Complement Activation Impairs Bacterial Clearance during Enterococcus faecalis Infection

Author:

Shehab El-Din Eman M. Rabie1,Elgaml Abdelaziz12,Ali Youssif M.13ORCID,Hassan Ramadan1

Affiliation:

1. Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

2. Department of Microbiology and Immunology, Faculty of Pharmacy, Horus University, New Damietta, Egypt

3. Department of Veterinary Medicine, School of Biological Sciences, University of Cambridge, Cambridge, United Kingdom

Abstract

Enterococcus faecalis infections are considered a major public health concern worldwide. The complement system has a crucial role in the protection against different microbial pathogens, including E. faecalis .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference46 articles.

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4. Agudelo Higuita NI, Huycke MM. 2014. Enterococcal disease, epidemiology, and implications for treatment. In Gilmore MS, Clewell DB, Ike Y, Shankar N (ed), Enterococci: from commensals to leading causes of drug resistant infection. Boston, MA.

5. Kristich CJ, Rice LB, Arias CA. 2014. Enterococcal infection-treatment and antibiotic resistance. In Gilmore MS, Clewell DB, Ike Y, Shankar N (ed), Enterococci: from commensals to leading causes of drug resistant infection. Boston, MA.

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