Affiliation:
1. Institute of Hygiene, University of Cologne, Cologne, Germany
Abstract
The minimal inhibitory concentrations of 32 antimicrobial agents were established for 73 strains of
Propionibacterium acnes
and four related species (
P. granulosum, P. avidum, Corynebacterium minutissimum
, and
C. parvum
). Most strains showed good susceptibility to those agents usually considered active against gram-positive organisms. With the exception of
C. minutissimum
, the strains tested revealed more or less identical susceptibility ranges. The lowest minimal inhibitory concentrations were observed with benzylpenicillin, ampicillin, cephalothin, rifampin, erythromycin, clindamycin, and minocycline.
C. minutissimum
was more susceptible to gentamicin, sisomicin, tobramycin, and fusidic acid but more resistant to most other drugs than were the other species examined.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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