Genome Sequence of the Anterograde-Spread-Defective Herpes Simplex Virus 1 Strain MacIntyre-Reference-Cited by-同舟云学术

Genome Sequence of the Anterograde-Spread-Defective Herpes Simplex Virus 1 Strain MacIntyre

Published:2014-12-24 Issue:6 Volume:2 Page:
ISSN:2169-8287
Container-title:Genome Announcements
language:en
Short-container-title:Genome Announc

Author:

Szpara Moriah L.¹²,Tafuri Yolanda R.¹,Parsons Lance³,Shreve Jacob T.²,Engel Esteban A.¹,Enquist L. W.¹³

Affiliation:

1. Department of Molecular Biology, the Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA

2. Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA

3. Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA

Abstract

ABSTRACT We used paired-end Illumina deep sequencing and de novo assembly to determine the genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a unique limitation in its neuronal spread, moving solely in the retrograde direction.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/genomeA.01161-14

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