Genome Sequence of a Cynomolgus Macaque Adenovirus (CynAdV-1) Isolate from a Primate Colony in the United Kingdom

Author:

Zeng Zhiwei1,Zhang Jing1,Jing Shuping1,Cheng Zetao1,Bofill-Mas Silvia2,Maluquer de Motes Carlos2,Hundesa Ayalkibet2,Girones Rosina2,Seto Donald3,Zhang Qiwei14

Affiliation:

1. Biosafety Level-3 Laboratory, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China

2. Section of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, University of Barcelona, Barcelona, Spain

3. Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, Virginia, USA

4. Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA

Abstract

ABSTRACT The genome sequence of a simian adenovirus from a cynomolgus macaque, denoted CynAdV-1, is presented here. Phylogenetic analysis supports CynAdV-1 in an independent clade, comprising a new simian adenovirus (SAdV) species. These genome data are critical for understanding the evolution and relationships of primate adenoviruses, including zoonosis and emergent human pathogens.

Funder

Excellent Young Teacher Training Plan of Guangdong Province

Young Top-notch Talents of the Guangdong Province Special Support Program

The Office of the Vice President for Research at George Mason University

China Scholarship Council

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Reference23 articles.

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2. Recombination of the epsilon determinant and corneal tropism: Human adenovirus species D types 15, 29, 56, and 69

3. Cross-Species Transmission of a Novel Adenovirus Associated with a Fulminant Pneumonia Outbreak in a New World Monkey Colony

4. A Novel Adenovirus Species Associated with an Acute Respiratory Outbreak in a Baboon Colony and Evidence of Coincident Human Infection

5. Simian adenovirus type 35 has a recombinant genome comprising human and simian adenovirus sequences, which predicts its potential emergence as a human respiratory pathogen

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