Draft Whole-Genome Sequence of a Catalase-Negative Staphylococcus aureus subsp. aureus (Sequence Type 25) Strain Isolated from a Patient with Endocarditis and Septic Arthritis

Author:

Berenger Byron1,Chen Justin2,Bernier Anne-Marie3,Bernard Kathryn45ORCID

Affiliation:

1. Alberta Provincial Laboratory for Public Health, Edmonton, Alberta, Canada

2. Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada

3. Department of Biology, Université de Saint-Boniface, Winnipeg, Manitoba, Canada

4. National Microbiology Laboratory, CSCHAH Site, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

5. Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada

Abstract

ABSTRACT Staphylococcus aureus strains without catalase activity are rare, challenging to identify with conventional biochemical methods, and, despite a supposed decreased pathogenicity, can still cause disease. The first whole-genome sequence of a catalase-negative S. aureus isolate causing severe recurrent invasive infection with two novel missense mutations in the katA gene is reported here.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Whole-Genome Sequencing for Bacterial Virulence Assessment;Application and Integration of Omics-powered Diagnostics in Clinical and Public Health Microbiology;2021

2. First description of a catalase-negative Staphylococcus aureus from a healthy carrier, with a novel nonsense mutation in the katA gene;International Journal of Medical Microbiology;2017-12

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