Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae-Reference-Cited by-同舟云学术

Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae

Published:2010-08 Issue:8 Volume:48 Page:2999-3002
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Woodford Neil¹,Eastaway Anne T.²,Ford Michael³,Leanord Alistair⁴,Keane Chloe⁴,Quayle Reinhard M.⁵,Steer Jane A.⁵,Zhang Jiancheng¹,Livermore David M.¹

Affiliation:

1. Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, Health Protection Agency, London, United Kingdom

2. HAI & Infection Control Group, Health Protection Scotland, Glasgow, United Kingdom

3. Microbiology Department, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

4. Microbiology Department, Southern General Hospital, Glasgow, United Kingdom

5. Department of Microbiology, Derriford Hospital, Plymouth, United Kingdom

Abstract

ABSTRACT We assessed the ability of three commercial systems to infer carbapenem resistance mechanisms in 39 carbapenemase-producing and 16 other carbapenem-resistant Enterobacteriaceae . The sensitivity/specificity values for “flagging” a likely carbapenemase were 100%/0% (BD Phoenix), 82 to 85%/6 to 19% (MicroScan), and 74%/38% (Vitek 2), respectively. OXA-48 producers were poorly detected, but all systems reliably detected isolates with KPC and most with metallo-carbapenemases.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00341-10

Reference40 articles.

1. Evaluation of Methods To Identify the Klebsiella pneumoniae Carbapenemase in Enterobacteriaceae

2. Aschbacher, R., M. Doumith, D. M. Livermore, C. Larcher, and N. Woodford. 2008. Linkage of acquired quinolone resistance (qnrS1) and metallo-β-lactamase (blaVIM-1) genes in multiple species of Enterobacteriaceae from Bolzano, Italy. J. Antimicrob. Chemother. 61 : 515-523.

3. Carmeli, Y., M. Akova, G. Cornaglia, G. L. Daikos, J. Garau, S. Harbarth, G. M. Rossolini, M. Souli, and H. Giamarellou. 2010. Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control. Clin. Microbiol. Infect. 16 : 102-111.

4. Spread of OXA-48-Positive Carbapenem-Resistant Klebsiella pneumoniae Isolates in Istanbul, Turkey

5. Cornaglia, G., and G. M. Rossolini. 2010. The emerging threat of acquired carbapenemases in Gram-negative bacteria. Clin. Microbiol. Infect. 16 : 99-101.

Cited by 87 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Carbapenem non-susceptibility overcalling by BD phoenix NMIC-500 panel;Journal of Infection and Chemotherapy;2024-10

2. Efficient Absorbance-Based Assay for Rapid Antibiotic Susceptibility Testing of Enterobacterales;Antibiotics;2024-09-06

3. β-lactam resistant phenotypes reported by VITEK®2 advanced expert systemTM (AES) compared to whole genome sequencing in Enterobacterales from North and Latin America;Diagnostic Microbiology and Infectious Disease;2024-09

4. Reliability of a Screening Method Using Antibiotic Disks to Detect Carbapenemases in Glucose‐Nonfermenting Gram‐Negative Microorganisms From Clinical Samples of a Regional Hospital in Southeastern Spain;Journal of Clinical Laboratory Analysis;2024-04

5. Carbapenem-resistant Klebsiella pneumoniae : the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge;Expert Review of Anti-infective Therapy;2024-01-30