Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae-Reference-Cited by-同舟云学术

Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae

Published:2010-08 Issue:8 Volume:48 Page:2999-3002
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Woodford Neil¹,Eastaway Anne T.²,Ford Michael³,Leanord Alistair⁴,Keane Chloe⁴,Quayle Reinhard M.⁵,Steer Jane A.⁵,Zhang Jiancheng¹,Livermore David M.¹

Affiliation:

1. Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, Health Protection Agency, London, United Kingdom

2. HAI & Infection Control Group, Health Protection Scotland, Glasgow, United Kingdom

3. Microbiology Department, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

4. Microbiology Department, Southern General Hospital, Glasgow, United Kingdom

5. Department of Microbiology, Derriford Hospital, Plymouth, United Kingdom

Abstract

ABSTRACT We assessed the ability of three commercial systems to infer carbapenem resistance mechanisms in 39 carbapenemase-producing and 16 other carbapenem-resistant Enterobacteriaceae . The sensitivity/specificity values for “flagging” a likely carbapenemase were 100%/0% (BD Phoenix), 82 to 85%/6 to 19% (MicroScan), and 74%/38% (Vitek 2), respectively. OXA-48 producers were poorly detected, but all systems reliably detected isolates with KPC and most with metallo-carbapenemases.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00341-10

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