Quantitative Approach To Assess Influenza A Virus Fitness and Transmission in Guinea Pigs

Author:

Danzy Shamika1,Lowen Anice C.12ORCID,Steel John12

Affiliation:

1. Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA

2. Emory-UGA Center of Excellence for Influenza Research and Surveillance (CEIRS), Atlanta, Georgia, USA

Abstract

Influenza pandemics occur when an IAV from nonhuman hosts enters the human population and adapts to give rise to a lineage capable of sustained transmission among humans. Despite recurring zoonotic infections involving avian- or swine-adapted IAVs, influenza pandemics occur infrequently because IAVs typically exhibit low fitness in a new host species.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference38 articles.

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5. World Health Organization. 2016. Tool for Influenza Pandemic Risk Assessment (TIPRA). https://www.who.int/influenza/publications/TIPRA_manual_v1/en/.

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