Author:
Grundström T,Normark S,Magnusson K E
Abstract
A quantitative study on outer membrane components was performed in a number of envelope mutants of Escherichia coli K-12 exhibition different permeability properties for antimicrobial agents. The envA1 allele causing an increased influx for both hydrophobic and hydrophilic drugs was found to be associated with a deficiency in the amount of lipopolysaccharides. The sefA1 envA1 double mutant was found to have a higher outer membrane buoyant density, apparently due to an increase in protein content. This double mutant was still low in lipopolysaccharide content.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference28 articles.
1. Identification of lipopolysaccharides and phospholipids of Escherichia coli in polyacrylamide gels;Bailey S. C.;J. Bacteriol.,1977
2. Phosphorus assay in column chromatography;Bartlett G. R.;J. Biol. Chem.,1959
3. Studies on Iysogenesis. I. The mode of phage liberation by Iysogenic Escherichia coli;Bertani G.;J. BacterioL,1951
4. A rapid method of total lipid extraction and purification;Bligh E. G.;Can. J. Biochem. Physiol.,1959
5. Characterization of lipopolysaccharides from Esdherichia coli K-12 mutants;Boman H. G.;J. Bacteriol.,1975
Cited by
36 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献