Affiliation:
1. Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York 10021
Abstract
ABSTRACT
Enterococcus faecalis
and
Enterococcus faecium
infections are increasingly difficult to treat due to high levels of resistance to antibiotics. PlyV12, a bacteriophage lytic enzyme, was isolated and shown to effectively kill both
E. faecalis
and
E. faecium
(including vancomycin-resistant strains), as well as other human pathogens. We propose its development and use as an alternative therapeutic tool.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
182 articles.
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