In Vitro Pharmacodynamic Characteristics of Nystatin Including Time-Kill and Postantifungal Effect-Reference-Cited by-同舟云学术

In Vitro Pharmacodynamic Characteristics of Nystatin Including Time-Kill and Postantifungal Effect

Published:2000-10 Issue:10 Volume:44 Page:2887-2890
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Gunderson Shana M.¹,Hoffman Holly¹,Ernst Erika J.¹,Pfaller Michael A.²,Klepser Michael E.¹

Affiliation:

1. College of Pharmacy1and

2. Department of Pathology, College of Medicine,2 The University of Iowa, Iowa City, Iowa 52242

Abstract

ABSTRACT Four Candida albicans isolates and six non- albicans Candida isolates were evaluated by time-kill methods to characterize the relationship between nystatin concentrations, the rate and extent of fungicidal activity, and the postantifungal effect (PAFE). Against Candida species, nystatin exhibits concentration-dependent fungicidal activity and a pronounced PAFE.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.44.10.2887-2890.2000

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