Precision Pandemic Preparedness: Improving Diagnostics with Metagenomics

Abstract

The threat posed by novel pandemics in the future remains active. Equipping our routine laboratory with clinical metagenomics to detect unknown threats early on offers a considerable advantage and may be feasible and scalable with the ability to identify complicated infectious diseases in routine care. Though several technical and regulatory challenges still exist, and clinical metagenomics may improve individual patient outcomes and provide earlier warning signs to improve pandemic preparedness.