Irreversible Loss of HIV-1 Proviral Competence in Myeloid Cells upon Suppression of NF-κB Activity-Reference-Cited by-同舟云学术

Irreversible Loss of HIV-1 Proviral Competence in Myeloid Cells upon Suppression of NF-κB Activity

Published:2022-06-22 Issue:12 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Peters Rebecca J.¹,Stevenson Mario²

Affiliation:

1. Department of Microbiology and Immunology, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA

2. Department of Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA

Abstract

Although HIV-1 infection can be suppressed using antiretroviral therapy, it cannot yet be cured. This is because HIV-1 integrates itself into host cells and may become dormant but also remains ready to emerge from such reservoirs when antiretroviral therapy stops.

Funder

CFAR

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Mental Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00484-22

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5. On the Road to a HIV Cure

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