Affiliation:
1. Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830
Abstract
Transforming deoxyribonucleic acid (DNA) from
Haemophilus influenzae
was exposed to X rays either in phosphate buffer or in 10% yeast extract. Relations between determinations of biological inactivation, DNA uptake by competent
H. influenzae
, integration of DNA into the competent cell genome, and induced single-and double-strand breaks indicate that transforming DNA is inactivated by the direct and the indirect effect of X radiation primarily because integration of DNA is prevented as a result of the production of double-strand breaks.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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