Caspofungin Susceptibility Testing of Candida inconspicua : Correlation of Different Methods with the Minimal Fungicidal Concentration-Reference-Cited by-同舟云学术

Caspofungin Susceptibility Testing of Candida inconspicua : Correlation of Different Methods with the Minimal Fungicidal Concentration

Published:2005-08 Issue:8 Volume:49 Page:3486-3488
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Majoros L.¹,Kardos G.¹,Szabó B.¹²,Sipiczki M.³

Affiliation:

1. Department of Medical Microbiology, University of Debrecen, Debrecen, Hungary

2. Faculty of Health Sciences, University of Debrecen, Debrecen, Hungary

3. Department of Genetics, University of Debrecen, Debrecen, Hungary

Abstract

ABSTRACT Minimal inhibitory and minimal fungicidal concentrations of caspofungin were determined for 48 Candida inconspicua isolates. By using CLSI (formerly NCCLS) methodology with the partial inhibition endpoint criterion, caspofungin exhibited a good fungicidal effect against C. inconspicua (the MIC 90 was 0.25 μg/ml and the minimum fungicidal concentration [MFC] was 0.5 μg/ml after 24 h). Total inhibition yielded falsely elevated MICs, exceeding even the respective MFCs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.8.3486-3488.2005

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