The Salmonella Pathogenicity Island 2-Encoded Type III Secretion System Is Essential for the Survival of Salmonella enterica Serovar Typhimurium in Free-Living Amoebae-Reference-Cited by-同舟云学术

The Salmonella Pathogenicity Island 2-Encoded Type III Secretion System Is Essential for the Survival of Salmonella enterica Serovar Typhimurium in Free-Living Amoebae

Published:2009-03-15 Issue:6 Volume:75 Page:1793-1795
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Bleasdale Benjamin¹,Lott Penelope J.¹,Jagannathan Aparna²,Stevens Mark P.²,Birtles Richard J.¹,Wigley Paul¹

Affiliation:

1. National Centre for Zoonosis Research and Department of Veterinary Pathology, University of Liverpool, Leahurst, Neston CH64 7TE, United Kingdom

2. Division of Microbiology, Institute for Animal Health, Compton RG20 7NN, United Kingdom

Abstract

ABSTRACT Free-living amoebae represent a potential reservoir and predator of Salmonella enterica . Through the use of type III secretion system (T3SS) mutants and analysis of transcription of selected T3SS genes, we demonstrated that the Salmonella pathogenicity island 2 is highly induced during S. enterica serovar Typhimurium infection of Acanthamoeba polyphaga and is essential for survival within amoebae.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02033-08

Reference25 articles.

1. Protozoan Acanthamoeba polyphaga as a Potential Reservoir for Campylobacter jejuni

2. Birtles, R. J., T. J. Rowbotham, R. Michel, D. G. Pitcher, B. Lascola, S. Alexiou-Daniel, and D. Raoult. 2000. ‘Candidatus Odyssella thessalonicensis’ gen. nov., sp. nov., an obligate intracellular parasite of Acanthamoeba species. Int. J. Syst. Evol. Microbiol.50:63-72.

3. Intracellular Growth in Acanthamoeba castellanii Affects Monocyte Entry Mechanisms and Enhances Virulence of Legionella pneumophila

4. Eriksson, S., S. Lucchini, A. Thompson, M. Rhen, and J. C. Hinton. 2003. Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica. Mol. Microbiol.47:103-118.

5. Gaze, W. H., N. Burroughs, M. P. Gallagher, and E. M. Wellington. 2003. Interactions between Salmonella typhimurium and Acanthamoeba polyphaga, and observation of a new mode of intracellular growth within contractile vacuoles. Microb. Ecol.46:358-369.

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enduring pathogenicity of African strains of Salmonella on plastics and glass in simulated peri-urban environmental waste piles;Journal of Hazardous Materials;2024-01

2. Pathogenic and Opportunistic Free-Living Amoebae: Agents of Human and Animal Disease;Manson's Tropical Diseases;2024

3. Salmonella Salamae and S. Waycross isolated from Nile perch in Lake Victoria show limited human pathogenic potential;Scientific Reports;2022-03-10

4. Cappable-Seq Reveals Specific Patterns of Metabolism and Virulence for Salmonella Typhimurium Intracellular Survival within Acanthamoeba castellanii;International Journal of Molecular Sciences;2021-08-23

5. Amoebae as Targets for Toxins or Effectors Secreted by Mammalian Pathogens;Toxins;2021-07-28