ColdZyme Maintains Integrity in SARS-CoV-2-Infected Airway Epithelia-Reference-Cited by-同舟云学术

ColdZyme Maintains Integrity in SARS-CoV-2-Infected Airway Epithelia

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Posch W.¹^ORCID,Vosper J.²,Zaderer V.¹,Noureen A.¹,Constant S.³,Bellmann-Weiler R.⁴,Lass-Flörl C.¹^ORCID,Wilflingseder D.¹^ORCID

Affiliation:

1. Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria

2. Institute of Medical Biochemistry, Geneva, Switzerland

3. Epithelix Sàrl, Geneva, Switzerland

4. University Hospital of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria

Abstract

Although our understanding of COVID-19 continuously progresses, essential questions regarding prophylaxis and treatment remain open. A hallmark of severe SARS-CoV-2 infection is a hitherto-undescribed mechanism leading to excessive inflammation and tissue destruction associated with enhanced pathogenicity and mortality.

Funder

Austrian Science Fund

Oesterreichische Nationalbank

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00904-21

Reference32 articles.

1. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein