Comparison of Oral Fluid Collectors for Use in a Rapid Point-of-Care Diagnostic Device-Reference-Cited by-同舟云学术

Comparison of Oral Fluid Collectors for Use in a Rapid Point-of-Care Diagnostic Device

Published:2004-09 Issue:5 Volume:11 Page:909-912
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Holm-Hansen Carol¹²³,Tong Gary¹²³,Davis Cheryl¹²³,Abrams William R.¹²³,Malamud Daniel¹²³

Affiliation:

1. Division for Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway

2. Department of Biochemistry

3. School of Dental Medicine, Department of Anatomy and Cell Biology, University of Pennsylvania, Philadelphia, Pennsylvania

Abstract

ABSTRACT Orally based diagnostic testing is emerging as an alternative, noninvasive method for analyzing a variety of analytes. These analytes include pathogens, antibodies, drugs, and nucleic acids. In the present study we developed a protocol for evaluation of collectors that could be used in orally based, point-of-care diagnostics. A performance comparison was carried out with a number of commercially available collectors, and their ability to deliver fluid, proteins, bacteria, and nucleic acid from pathogens compatible with PCR was assessed. The collectors were all capable of picking up and delivering test materials, albeit at various levels.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.11.5.909-912.2004

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