Kinetics of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibodies in 271 Laboratory-Confirmed Cases of SARS
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Published:2004-07
Issue:4
Volume:11
Page:792-794
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ISSN:1556-6811
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Container-title:Clinical and Vaccine Immunology
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language:en
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Short-container-title:Clin Vaccine Immunol
Author:
He Zhongping1234, Dong Qingming1234, Zhuang Hui1234, Song Shujing1234, Peng Guoai1234, Luo Guangxiang1234, Dwyer Dominic E.1234
Affiliation:
1. Beijing Ditan Hospital, Beijing 100011 2. Department of Microbiology, Peking University Health Science Center, Beijing 100083, People's Republic of China 3. Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky 40536-0298 4. Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales 2145, Australia
Abstract
ABSTRACT
The sensitivities and specificities of an immunofluorescence assay and an enzyme immunoassay for detection of antibodies specific for severe acute respiratory syndrome coronavirus (SARS-CoV) were compared for 148 laboratory-confirmed SARS cases. The appearance and persistence of SARS-CoV-specific antibodies were assessed, with immunoglobulin G detected in 59% of samples collected within 14 days and persisting for 60 to 95 days after the onset of illness.
Publisher
American Society for Microbiology
Subject
Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy
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