Affiliation:
1. Laboratoire de Virologie du CHU et Groupe Régional d’Observation de la Grippe Rhône-Alpes, Hospices Civils de Lyon, Domaine Rockefeller, 69373 Lyon Cedex 08, France
Abstract
ABSTRACT
In this prospective study, nasal swab samples from patients with acute respiratory infections were evaluated for the presence of
Mycoplasma pneumoniae
. This PCR-plus-hybridization-based detection was associated with the detection of other viral agents. During the five winter surveillance periods, 3,897 samples were collected by 75 medical practitioners participating in the Groupe Régional d’Observation de la Grippe surveillance network in Rhône-Alpes (France).
M. pneumoniae
was detected in 283 samples (7.3%); its rate of detection ranged from 10.1 to 2.0% over the five periods, and it was the second most frequently isolated pathogen during the survey, after influenza A. Three high-prevalence winters were observed, yielding an early winter peak of
M. pneumoniae
infection which was observed in all age groups. No statistically significant difference was detected between rates of infections in the different age groups, but
M. pneumoniae
infection was significantly related to lower respiratory tract infection during periods of high prevalence. This study defined the frequency of
M. pneumoniae
detection from nasal swab specimens in patients with acute respiratory infections, confirming its high prevalence and the presence of large outbreaks due to this pathogen.
Publisher
American Society for Microbiology
Cited by
62 articles.
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