Comparison of Quantitations of Viral Load in Varicella and Zoster

Author:

Kimura Hiroshi1,Kido Shinji2,Ozaki Takao2,Tanaka Naoko1,Ito Yoshinori1,Williams Richard K.3,Morishima Tsuneo1

Affiliation:

1. Department of Pediatrics, Nagoya University School of Medicine, Nagoya,1 and

2. Department of Pediatrics, Showa Hospital, Aichi,2 Japan, and

3. Medical Virology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland3

Abstract

ABSTRACT The pathogenesis of varicella and zoster and the effects of antiviral treatment were investigated using real-time PCR for varicella-zoster virus (VZV) DNA in skin lesions and peripheral blood. A higher occurrence of viremic VZV DNA was observed in varicella than in zoster. Acyclovir treatment resulted in marked suppression of viremia in varicella.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference7 articles.

1. Arvin A. M. Varicella-zoster virus Fields virology 3rd ed. Fields B. N. Knipe D. M. Howley P. M. Chanock R. M. Melnick J. L. Monath T. P. Straus S. E. 1996 2547 2585 Lippincott-Raven Publishers Philadelphia Pa

2. Severity of viremia and clinical findings in children with varicella;Asano Y.;J. Infect. Dis.,1990

3. A controlled trial of acyclovir for chickenpox in normal children;Dunkle L. M.;N. Engl. J. Med.,1991

4. Recombinant varicella-zoster virus glycoproteins E and I: immunologic responses and clearance of virus in a guinea pig model of chronic uveitis;Kimura H.;J. Infect. Dis.,1998

5. Investigation of varicella-zoster virus infection of lymphocytes by in situ hybridization

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3