Usefulness of Urinary Antigen Detection by an Immunochromatographic Test for Diagnosis of Pneumococcal Pneumonia in Children-Reference-Cited by-同舟云学术

Usefulness of Urinary Antigen Detection by an Immunochromatographic Test for Diagnosis of Pneumococcal Pneumonia in Children

Published:2003-05 Issue:5 Volume:41 Page:2161-2163
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Domínguez J.¹,Blanco S.¹,Rodrigo C.²,Azuara M.²,Galí N.¹,Mainou A.²,Esteve A.³,Castellví A.⁴,Prat C.¹,Matas L.¹,Ausina V.¹

Affiliation:

1. Servei de Microbiologia

2. Servei de Pediatria

3. Centre d'Estudis Epidemiològics sobre la SIDA de Catalunya (CEESCAT)

4. Servei de Cirurgia Pediàtrica, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Spain

Abstract

ABSTRACT We evaluated an immunochromatographic assay detecting pneumococcal antigen in urine samples from children diagnosed with pneumococcal pneumonia. The sensitivity and specificity of the immunochromatographic test with nonconcentrated urine (NCU) were 86.7 and 62.9%, respectively; with concentrated urine (CU), they were 100 and 11.7%, respectively. Pneumococcal antigen was also detected in 42.5% of NCU and 87.1% of CU samples from nasopharyngeal carriers. This is a nonspecific test for the diagnosis of pneumococcal pneumonia in children, particularly the very young.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.41.5.2161-2163.2003

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