Morphogenesis of poliovirus. IV. existence of particles sedimenting at 150S and having the properties of provirion

Author:

Guttman N,Baltimore D

Abstract

An apparent precursor to the poliovirion that cosediments with the virion at 150S was identified by its content of VP-0. It has properties previously associated with the provirion, a structure that sedimented at 125S, and it may be an alternate form of provirion. Like virions, the 150S precursor binds to and elutes from cells, after which it sediments at about 125S.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference13 articles.

1. Baltimore D. 1969. The replication of picornaviruses p. 101-176. In H. B. Levy (ed.) The biochemistry of viruses. Marcel Dekker New York.

2. Aspects of the synthesis of poliovirus RNA and the formation of viral particles;Baltimore D.;Virology,1966

3. A film detection method for tritium-labeled proteins and nucleic acids in polyacrylamide gels;Bonner W. M.;Eur. J. Biochem.,1974

4. Early interactions between poliovirus and ERK cells. Some observations on the nature and significance of the rejected particles;Fenwick M. L.;Virology,1962

5. Morphogenesis of poliovirus. II. Demonstration of a new intermediate, the provirion;Fernandez-Tomas C. B.;J. Virol.,1973

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