BacA-Mediated Bleomycin Sensitivity in Sinorhizobium meliloti Is Independent of the Unusual Lipid A Modification-Reference-Cited by-同舟云学术

BacA-Mediated Bleomycin Sensitivity in Sinorhizobium meliloti Is Independent of the Unusual Lipid A Modification

Published:2006-04-15 Issue:8 Volume:188 Page:3143-3148
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Ferguson Gail P.¹,Jansen An²,Marlow Victoria L.¹,Walker Graham C.²

Affiliation:

1. Institute of Structural and Molecular Biology and Centre for Science at Extreme Conditions, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JR, United Kingdom

2. Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139

Abstract

ABSTRACT Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.188.8.3143-3148.2006

Reference18 articles.

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