Prediction of Antibiotic Susceptibility for Urinary Tract Infection in a Hospital Setting-Reference-Cited by-同舟云学术

Prediction of Antibiotic Susceptibility for Urinary Tract Infection in a Hospital Setting

Published:2020-06-23 Issue:7 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hebert Courtney¹²,Gao Yuan³,Rahman Protiva⁴,Dewart Courtney⁵,Lustberg Mark²,Pancholi Preeti⁶,Stevenson Kurt²,Shah Nirav S.⁷,Hade Erinn M.⁸⁹

Affiliation:

1. Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, Ohio, USA

2. Division of Infectious Diseases, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

3. Division of Biostatistics, The Ohio State University College of Public Health, Columbus, Ohio, USA

4. Department of Computer Science and Engineering, The Ohio State University College of Engineering, Columbus, Ohio, USA

5. Division of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA

6. Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

7. Division of Infectious Diseases, NorthShore University HealthSystem, Evanston, Illinois, USA

8. Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

9. Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

Abstract

Empiric antibiotic prescribing can be supported by guidelines and/or local antibiograms, but these have limitations. We sought to use data from a comprehensive electronic health record to use statistical learning to develop predictive models for individual antibiotics that incorporate patient- and hospital-specific factors. This paper reports on the development and validation of these models with a large retrospective cohort. This was a retrospective cohort study including hospitalized patients with positive urine cultures in the first 48 h of hospitalization at a 1,500-bed tertiary-care hospital over a 4.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Center for Advancing Translational Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02236-19

Reference20 articles.

1. Demonstration of the Weighted-Incidence Syndromic Combination Antibiogram: An Empiric Prescribing Decision Aid

2. Locally Derived versus Guideline-Based Approach to Treatment of Hospital-Acquired Pneumonia in the Trauma Intensive Care Unit