BACTERIOPHAGE COMMON TO PASTEURELLA PESTIS AND ESCHERICHIA COLI

Author:

Hertman I.1

Affiliation:

1. Israel Institute for Biological Research, Ness Ziona, Israel

Abstract

Hertman, I. (Israel Institute for Biological Research, Ness Ziona, Israel). Bacteriophage common to Pasteurella pestis and Escherichia coli . J. Bacteriol. 88: 1002–1005. 1964.—Phage Y of Pasteurella pestis and phage T 3 of Escherichia coli are serologically related and have common bacterial hosts. Anti-Y serum neutralizes the homologous phage and phage T 3 to a similar extent. Anti-Y serum, absorbed with T 3 , still neutralizes the activity of phage Y for P. pestis , but not the activity for E. coli B/r. A mutant of phage Y was isolated from turbid plaques formed on P. pestis at 27 C. This mutant infected P. pestis only if this organism had been grown at 27 C; it lost its infectivity towards E. coli B/r and was not neutralized by anti-T 3 serum. From this phage, additional mutants were isolated on P. pestis , some of which were infective for both P. pestis and E. coli B/r and some of which remained infective for P. pestis only. The reacquired infectivity for E. coli B/r was neutralized by anti-T 3 serum. The name T 3 P is suggested for phage Y.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference10 articles.

1. ADAMS M. H. 1959. Bacteriophages. Interscience Publishers Inc. New York.

2. Genetic variants of bacteriophage T3;EISENSTARK A.;Virology,1961

3. Sensibilitd des bacilles pesteux et pseudotuberculeux d'une part de groupe colidesint 6rique d'autre part aux bact 6rio-phages;GIRARD G.;Ann. Inst. Pasteur,1943

4. A study on Pesticin biosynthesis;HERTMAN I.;J. Gen. Microbiol.,1959

5. Immunogenetic dissection of T5 bacteriophage tail;LANNI F.;Science,1958

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