Affiliation:
1. National Caries Program, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014
Abstract
A total of 82 strains of
Streptococcus mutans
representing serotypes
a
through
g
were tested for susceptibility to erythromycin, penicillin, methicillin, lincomycin, tetracycline, vancomycin, gentamicin, streptomycin, neomycin, kanamycin, bacitracin, and polymyxin B. Strains included stock cultures and isolates from human and animal dental plaque. Minimal inhibitory concentrations were determined by a broth-microdilution procedure. The major differences in antibiotic susceptibility observed among the serotypes resulted with antibiotics which act on the cell surface. Bacitracin was most active against serotype
a
strains and polymyxin B against serotype
b
strains. Serotypes
a, d
, and
g
were less susceptible than the other serotypes to methicillin.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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