Monoclonal Antibodies Opsonize Burkholderia spp. and Reduce Intracellular Actin Tail Formation in a Macrophage Infection Assay-Reference-Cited by-同舟云学术

Monoclonal Antibodies Opsonize Burkholderia spp. and Reduce Intracellular Actin Tail Formation in a Macrophage Infection Assay

Published:2021-10-12 Issue:21 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Taylor A.¹²,Jenner D.¹,Rowland C.¹,Laws T.¹,Norville I.¹,Prior J.¹³⁴

Affiliation:

1. Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom

2. London School of Hygiene and Tropical Medicine (LSHTM), London, United Kingdom

3. University of Exeter, Exeter, United Kingdom

4. University of Southampton, Southampton, United Kingdom

Abstract

Melioidosis is difficult to treat successfully due to the causal bacterium being resistant to many classes of antibiotics, therefore limiting available therapeutic options. New and improved therapies are urgently required to treat this disease.

Funder

Ministry of Defence

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00244-21

Reference41 articles.

1. Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis

2. Melioidosis, the great mimicker: a report of 10 cases from Malaysia;Yee KC;J Trop Med Hyg,1988

3. Melioidosis: the great mimicker

4. Melioidosis: acute and chronic disease, relapse and re-activation

5. Recurrent Melioidosis in Patients in Northeast Thailand Is Frequently Due to Reinfection Rather than Relapse

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