Effective Rapid Diagnosis of Bacterial and Fungal Bloodstream Infections by T2 Magnetic Resonance Technology in the Pediatric Population-Reference-Cited by-同舟云学术

Effective Rapid Diagnosis of Bacterial and Fungal Bloodstream Infections by T2 Magnetic Resonance Technology in the Pediatric Population

Published:2022-10-19 Issue:10 Volume:60 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Lucignano Barbara¹,Cento Valeria²³,Agosta Marilena¹^ORCID,Ambrogi Federico⁴,Albitar-Nehme Sami¹^ORCID,Mancinelli Livia¹,Mattana Giordana¹,Onori Manuela¹,Galaverna Federica⁵,Di Chiara Luca⁶,Fragasso Tiziana⁶,Bianchi Roberto⁷,Tortora Francesca⁷,Auriti Cinzia⁸^ORCID,Dotta Andrea⁸,Cecchetti Corrado⁹,Perdichizzi Salvatore⁹,Raponi Massimiliano¹⁰,Onetti Muda Andrea¹¹,Nerini Molteni Silvia¹²,Villani Alberto¹³,Locatelli Franco⁵¹⁴,Perno Carlo Federico¹^ORCID,Bernaschi Paola¹

Affiliation:

1. Unit of Microbiology and Diagnostic Immunology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

2. Department of Biomedical Sciences, Humanitas University, Milan, Italy

3. IRCCS Humanitas Research Hospital, Milan, Italy

4. Department of Clinical and Community Sciences, Università degli Studi di Milano, Milan, Italy

5. Department of Pediatric Hematology and Oncology and of Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

6. Department of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

7. Anesthesia and Critical Care Medicine, ARCO Rome, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

8. Neonatal Intensive Care Unit, Medical and Surgical Department of the Fetus Newborn and Infant, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

9. Pediatric Intensive Care Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

10. Health Directorate, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

11. Department of Laboratories, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

12. Chemical-Clinical and Microbiological Analysis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

13. General Pediatrics Unit, Pediatric Emergency and General Pediatrics Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

14. Sapienza University of Rome, Rome, Italy

Abstract

Children are prone to bloodstream infections (BSIs), the rapid and accurate diagnosis of which is an unmet clinical need. The T2MR technology is a direct molecular assay for identification of BSI pathogens, which can help to overcome the limits of blood culture (BC) such as diagnostic accuracy, blood volumes required, and turnaround time.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.00292-22

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