The Type IX Secretion System Is Required for Virulence of the Fish Pathogen Flavobacterium psychrophilum-Reference-Cited by-同舟云学术

The Type IX Secretion System Is Required for Virulence of the Fish Pathogen Flavobacterium psychrophilum

Published:2020-08-03 Issue:16 Volume:86 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Barbier Paul¹,Rochat Tatiana²,Mohammed Haitham H.¹³,Wiens Gregory D.⁴^ORCID,Bernardet Jean-François²,Halpern David⁵,Duchaud Eric²^ORCID,McBride Mark J.¹^ORCID

Affiliation:

1. Department of Biological Sciences, University of Wisconsin—Milwaukee, Milwaukee, Wisconsin, USA

2. Université Paris-Saclay, INRAE, UVSQ, VIM, Jouy-en-Josas, France

3. Department of Aquatic Animal Medicine and Management, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt

4. National Center for Cool and Cold Water Aquaculture, Agricultural Research Service, USDA, Kearneysville, West Virginia, USA

5. Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France

Abstract

Bacterial cold-water disease, caused by F. psychrophilum , is a major problem for salmonid aquaculture. Little is known regarding the virulence factors involved in this disease, and control measures are inadequate. A targeted gene deletion method was adapted to F. psychrophilum and used to demonstrate the importance of the T9SS in virulence. Proteins secreted by this system are likely virulence factors and targets for the development of control measures.

Funder

National Science Foundation

U.S. Department of Agriculture

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00799-20

Reference87 articles.

1. Virulence mechanisms in Cytophaga psychrophila and other Cytophaga-like bacteria pathogenic for fish